Galactomannan antigenemia in invasive aspergillosis
نویسندگان
چکیده
منابع مشابه
Galactomannan antigenemia for the diagnosis of invasive aspergillosis in neutropenic patients with hematological disorders.
OBJECTIVES Invasive aspergillosis (IA) is among the most common invasive fungal infections in neutropenic patients with hematological disorders in the authors' institution, King Chulalongkorn Memorial Hospital (KCMH), Bangkok, Thailand Previous studies have reported the Aspergillus galactomannan enzyme immunosorbent assay (GMEIA) may be a useful diagnostic tool for IA. The authors evaluated the...
متن کاملGalactomannan detection for invasive aspergillosis in immunocompromized patients.
BACKGROUND Invasive aspergillosis (IA) is the most common life-threatening opportunistic invasive mycosis in immunocompromized patients. A test for IA needs to be not too invasive and not too big a burden for the already weakened patient. The serum galactomannan ELISA seems to have potential for both requirements. OBJECTIVES To obtain summary estimates of the diagnostic accuracy of galactoman...
متن کاملDiscordant rise in galactomannan antigenemia in a patient with resolving Aspergillosis, renal failure, and ongoing hemodialysis.
We describe the case of a patient with improving invasive aspergillosis and paradoxically rising serum galactomannan levels in the presence of chronic renal failure and ongoing hemodialysis. Dialysate tested negative for galactomannan, demonstrating the inability of treatments such as hemodialysis to clear Aspergillus antigen from serum. In patients with renal failure and aspergillosis, rising ...
متن کاملUsing the galactomannan assay in the diagnosis of invasive aspergillosis.
Aspergillus species are ubiquitous molds to which humans are commonly exposed. Of approximately 180 species, it is estimated that 34 are medically significant.1 Most persons who come in contact with the fungus remain asymptomatic. However, some experience mild morbidity demonstrated by recurrent sinusitis, asthma exacerbations, or allergic bronchopulmonary aspergillosis. Patients who are immuno...
متن کاملSerum galactomannan levels in the diagnosis of invasive aspergillosis
BACKGROUND/AIMS In this study, the sensitivity-specificity of galactomannan-enzyme immunoassay (GM-EIA) with a cut-off value of 0.5 for a single, two, or three consecutive positivity in the diagnosis of invasive pulmonary aspergillosis (IPA) in neutropenic patients with hematological malignancy was investigated. METHODS IPA was classified as "proven," "probable," or "possible" as described in...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 1979
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.25.1.357-365.1979